Application of Deep Reinforcement Learning to Event-Triggered Control for Networked Artificial Pancreas Systems

· Source: stat.ML updates on arXiv.org · Field: Technology & Digital — Artificial Intelligence & Machine Learning, Robotics & Autonomous Systems, Health & Medical Research · Depth: Expert, extended

Summary

This paper introduces a deep reinforcement learning (DRL)-based event-triggered controller, called CGM-ETPPO, for networked artificial pancreas (AP) systems. The goal is to maintain blood glucose levels within the 70-180 mg/dL target range while significantly reducing communication frequency and energy consumption. Unlike existing DRL methods that assume periodic updates or jointly learn insulin dosing and update timing, CGM-ETPPO decouples these tasks by using a rule-based event-triggering mechanism based on changes in continuous glucose monitor (CGM) values. This approach formulates the problem as a semi-Markov decision process (SMDP), extending a standard DRL algorithm to handle irregular decision intervals. Numerical experiments using the UVA/Padova T1D simulator with 10 virtual adult patients demonstrate that CGM-ETPPO achieves over 90% Action Update Reduction Rate (AURR) and comparable Time in Range (TIR) to well-tuned PID controllers, outperforming hierarchical DRL methods in training success.

Key takeaway

For AI Scientists and Machine Learning Engineers developing control systems for medical devices, adopting a decoupled, rule-based event-triggered DRL approach can significantly enhance energy efficiency without compromising control performance. Your teams should consider formulating problems with irregular decision intervals as Semi-Markov Decision Processes and extending standard DRL algorithms to manage complexity, especially when deploying on resource-constrained wearable devices like artificial pancreas systems.

Key insights

A DRL-based event-triggered controller for artificial pancreas systems improves energy efficiency by decoupling insulin dosing from update timing.

Principles

Method

The CGM-ETPPO algorithm extends PPO for SMDPs, using a rule-based event-triggering mechanism based on CGM value changes to determine insulin infusion rate updates.

In practice

Topics

Code references

Best for: AI Scientist, Machine Learning Engineer, Research Scientist

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Editorial summary, takeaway, and curation by AIssential. Original article published by stat.ML updates on arXiv.org.