v156: Proceedings of COMPAY 2021
Summary
The MICCAI Workshop on Computational Pathology (Volume 156, 2021) presented significant advancements in applying artificial intelligence to digital pathology, focusing on enhancing diagnostic and prognostic capabilities. Papers explored diverse deep learning and multiple instance learning (MIL) approaches for tasks such as molecular subtype prediction in breast cancer, ER & PR status prediction from H&E Whole Slide Images (WSIs), and glioma sub-type classification. Key methodologies included improving Mask R-CNN for nuclei instance segmentation, multi-scale regional attention Deeplab3+ for plasma cell segmentation, and deep learning for interpretable end-to-end survival prediction in gastrointestinal cancer histopathology. Innovations also covered random multi-channel image synthesis for multiplexed immunofluorescence, robust quad-tree based WSI registration, unsupervised domain adaptation for histopathological cell segmentation, and graph analytics toolkits like HistoCartography. The workshop highlighted a broad spectrum of computational techniques, including self-supervised learning for dMMR/MSI detection and sparse convolutional context-aware MIL, demonstrating progress across various cancer types and imaging modalities.
Key takeaway
This MICCAI workshop volume highlights significant deep learning advances in computational pathology, addressing critical tasks from nuclei segmentation and cancer classification to molecular subtype and survival prediction. Papers introduce novel methods like SparseConvMIL, Multi-scale Graph Networks, and self-supervised learning, improving accuracy and interpretability across H&E and multiplexed imaging. These innovations offer pathologists and researchers tools for enhanced diagnostic precision, biomarker discovery, and prognostic assessment in various cancers, including breast, gastrointestinal, and thyroid.
Topics
- Computational Pathology
- Deep Learning
- Whole Slide Imaging
- Multiple Instance Learning
- Cancer Diagnosis
Code references
- bmdeep/SegPC2021
- butkej/MIL4Cyto
- KatherLab/Survival
- histocartography/histocartography
- MarvinLer/SparseConvMIL
Best for: Computer Vision Engineer, AI Scientist, Machine Learning Engineer, Research Scientist
Related on AIssential
Editorial summary, takeaway, and curation by AIssential. Original article published by Proceedings of Machine Learning Research.